pearGRN (Pear Integrative Gene Regulatory Network Database) is a comprehensive resource designed to consolidate various omics regulatory networks, facilitating the retrieval of gene regulatory relationships and protein interactions. It provides a platform to predict key genes associated with important breeding-related traits.

The database offers several tools including BLAST, Expression, Jbrowse, Gene Search, Node Search, Network Creation, Network Comparison, TF Regulation, Interact Finder, TraitConnect and ML Predictor, making it an essential resource for researchers in pear genetics and genomics.

PearGRN is hosted by Central of Pearl Engineering Technology Research at Nanjing Agricultural University and aims to support advanced genetic research and breeding projects in pears.

Citations:

Network	Node number	Edge number	Transitivity	Avg. of distance	Modules (>=5 genes)	Hub gene
Fat CoE Network	35007	2658240	0.371	2.75	678	3496
Slim CoE Network (HC)	29723	351635	0.283	4.09	1693	2955
Slim CoE Network (LC)	31929	3896398	0.302	2.67	422	3192
PWM Network	39473	395509	0.004	2.61	101	3799
ATAC-PWM Network	9717	194238	0.012	2.51	22	956
Pcorr Network	2304	269130	1	1	21	492
cPPI Network	6790	64003	0.117	3.43	269	670
3D Inter Network	3032	5237	0.019	2.59	228	261
3D Intra Network	8591	16743	0.045	3.75	559	805
3D Network	10964	21980	0.05	4.55	737	1059
Nocoding Network	25700	1626783	0.8	5.24	929	2484
Interactome Network	8666	333115	0.944	3.31	262	825
TF-target Regulatory Network	44574	1019312	0.015	2.56	761	4425
Integrative Network	45933	2871763	0.257	2.57	926	4586